The Ubiquinol form of CoQ10 is difficult to commercially manufacture because the coenzyme is easily oxidized in the air, which converts it back to the inactive (conventional) ubiquinone form.
After years of research and using advanced technology, Kaneka was able to perfect a stabilization process that allows Ubiquinol to remain in its reduced, readily usable form without converting back into ordinary ubiquinone during the encapsulation process.